anandamide

It is a Fatty acid ethanolamide of the polyinsaturated type (so it goes through the two-step catalysis process of 1) transport into the cell followed by 2) hydrolisis by FAAH). Although it seems its degradation (and of the other FAEs) follows an alternative mechanism in the duodenum [1]. It is an endogenous cannabinoid.

[1]

D. Fegley et al., “Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3′-carbamoyl-biphenyl-3-yl ester (URB597): Effects on anandamide and oleoylethanolamide deactivation,” The journal of pharmacology and experimental therapeutics, vol. 313, no. 1, pp. 352–358, Apr. 2005, doi: 10.1124/jpet.104.078980. Available: https://www.sciencedirect.com/science/article/pii/S0022356524319238. [Accessed: Nov. 11, 2025]