Role of Reactive Oxygen Species in Epilepsy I
=============================================
Source: Role of Reactive Oxygen Species in Epilepsy I
- recurrent seizures cause:
- production of reactive oxygen species
- altered gluthatione [GSH] redox status
- alterations in endogenous antioxidants:
- catalase, gluthatione, peroxidase (GPx)
- rodent genetically deficient on super oxide dismutase (SOD2) or thioredoxin 2 (TXN2) exhibit spontaneous seizures